Upper Weyanoke is a historic plantation house located near Charles City, Charles City County, Virginia. The property contains a one-and-a-half-story cottage built about 1815, and a larger two-story Greek Revival style residence erected in 1858-59. The cottage was probably built by John Minge as a two-room dependency to a now-vanished main dwelling. The main house was built for Robert Douthat, and is a two-story brick dwelling with a side-hall plan typically utilized in urban homes, rather than rural plantation houses.

It was added to the National Register of Historic Places in 1980.